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In-Process:
• Bio-Tech Bubble Analysis
• Corrosion Analysis
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Volume 01, Edition 01 |
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WELCOME to the premier issue of
“The In Situ View Newsletter”.
It is the goal of this publication to discuss industry issues, challenges, problems and solutions that are encountered primarily in the pharmaceutical, biochemical and chemical process industries. We intend to provide the latest in product information and applicable research data. We encourage your comments pro or con on any of our topics and welcome suggestions for future articles.
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INDUSTRY ISSUES
This is an interview with Marc Singer
Assistant Director for Technology
at The Institute for Corrosion and Multiphase Technology
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What is the function of your department?
The Institute for Corrosion and Multiphase Technology (ICMT) has established itself as a leading facility for the investigation of CO2 corrosion of mild steel as related to the oil and gas industry. We have been conducting cutting edge research in this area for more than ten years now. However, as we are fully dependant on the Ohio University, our primary function remains to educate and train highly competent students who will implement and disseminate this knowledge throughout the corrosion engineering community.
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What are industry issues that you respond to?
The ICMT is entirely funded by the private sector and its research focus is driven exclusively by the current industry needs. Most of our medium and long term research projects are related the study of localized corrosion. This phenomenon is always linked to the presence of scale or deposit on the pipe surface. Therefore, corrosion product formation/dissolution involving CO2/H2S mixtures, corrosion under deposits related to sand settling or microbiologically induced corrosion (MIC) are the most serious issues of the moment. In addition, the ICMT is also involved in an extensive multiphase flow research project with the aim of defining the flow regime of hydrocarbon/water mixture.
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Water condensation on metal coupon |
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What are the things you are currently working on?
We are currently working on a project linked to the Top of the Line Corrosion (TLC) which is a type of internal corrosion that happens in a wet gas line and in dewing conditions. The condensation regime (or the way that the droplets of liquid form at the top of the line from condensation of the vapor) is a critical parameter needed to access correctly the resulting corrosion attack. In this particular field, in-situ observation of the condensation/corrosion process has already proven to be a very valuable source of information.
www.corrosioncenter.org |
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ARTICLES & PAPERS
Article appearing in Bioprocess BiosystemEngineering DOI 10.1007/s00449-007-0127-y
Beth Junker, and Walter Maciejak Fermentation and Development Operations, Merck Research Laboratories, Rahway, NJ
Feasibility of an In Situ Measurement Device for Bubble
Size and Distribution. Copyright Springer-Vertag 2007
Abstract The feasibility of in situ measurement device for bubble size and distribution was explored. A novel in situ probe measurement system, the EnviroCam®, was developed. Where possible, this probe incorporated strengths, and minimized weaknesses of historical and currently available real-time measurement methods for bubbles. The system was based on a digital, high-speed, high resolution, modular camera system, attached to a stainless steel shroud, compatible with standard Ingold ports on fermenters.
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Still frames and/or video were produced, capturing bubbles passing through the notch of the shroud. An LED light source was integral with the shroud. Bubbles were analyzed using customized commercially available image analysis software and standard statistical methods. Using this system, bubble sizes were measured as a function of various operating parameters (e.g., agitation rate, aeration rate) and as a function of media properties (e.g., viscosity, antifoam, cottonseed flour, and microbial/animal cell broths) to demonstrate system performance and its limitations. For selected conditions, mean bubble size changes qualitatively compared favorably with published relationships.
For info on this article please email sfetters@envirocam.net
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NEW PRODUCTS
EnviroCam Inc. announces new products for October 2007
Corrosion Analysis
Designed specifically for corrosion analysis applications The EnviroCam® BS3 system configured for corrosion Analysis is ideal for pipeline and tank applications. The new system provides real time in situ corrosion analysis, inspection and historical recording of data using high resolution photo microscopy. Designed to operate in harsh environments this system can be permanently mounted and reside in the process, or be inserted through ports or valves to analyze different areas of the process.
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Bubble Analysis
When installed in a bioreactor/fermenter this system provides in situ real time remote observation, bubble analysis, process verification and historical recording of biochemical/pharmaceutical processes. The EnviroCam® FX3 system configured for Bubble Analysis offers general observation, sauter mean, gas hold up and a coefficient for interfacial area in a well mixed media. The system is compatible with process materials; cip/sip cycles and lends itself to process and PAT applications
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NEWS & NOTES
EnviroCam Inc. will be exhibiting at these upcoming shows. 2008 Interphex/Biotechnica US Conference on March, 26 - 28, 2008 at The Convetion Center, Philadelphia.The EnviroCam and the latest in bubble/cell analalytical software will be demonstrated. Visit us at booth 6423
2008 Nace Convention Corrosion Conference and EXPO, May, 16 - 20, 2008 at The Ernest N Morial Convention Center, New Orleans, Louisianna,The EnviroCam and the latest in corrosion analysis software will be demonstrated.
Contact: Steve Fetters
EnviroCam Inc., 2950 Unit “N” Advance Lane
Colmar PA.18915
Office (215) 996-1957 • Cell (267) 664-7188
If you no longer wish to receive email about EnviroCam®, you may unsubscribe by clicking this link.
Please put “Unsubscribe” in the title bar.
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EnviroCam Inc.
2950 Unit “N” Advance Lane
Colmar, PA 18915
Phone 215.996.1957 •
Fax 215.996.0666
Contact: Steve Fetters
sfetters@envirocam.net |
